Browsing Department of Clinical Medicine by Title
Now showing items 1206-1225 of 2116
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Liver elastography in healthy children using three different systems - how many measurements are necessary?
(Journal article; Peer reviewed, 2020-12-21)Purpose Liver elastography is increasingly being applied in screening for and follow-up of pediatric liver disease, and has been shown to correlate well with fibrosis staging through liver biopsy. Because time is of the ... -
Liver Elastography in Primary Sclerosing Cholangitis Patients Using Three Different Scanner Systems
(Journal article; Peer reviewed, 2020)The aim of the study described here was to characterize three different liver elastography methods in primary sclerosing cholangitis (PSC) patients, for the first time exploring 2-D shear wave elastography (2-D-SWE) in PSC ... -
Liver X receptors induce antiproliferative effects in basal-like breast cancer
(Journal article; Peer reviewed, 2023)Liver X receptors (LXRs) are nuclear transcription factors important in the regulation of cholesterol transport, and glucose and fatty acid metabolism. The antiproliferative role of LXRs has been studied in a variety of ... -
The liver-first approach for synchronous colorectal liver metastases: A systematic review and meta-analysis of completion rates and effects on survival
(Journal article; Peer reviewed, 2021)Background: Patients presenting with synchronous colorectal liver metastases are increasingly being considered for a curative treatment, and the liver-first approach is gaining popularity in this context. However, little ... -
Local Treatment of Recurrent Renal Cell Carcinoma May Have a Significant Survival Effect Across All Risk-of-recurrence Groups
(Journal article; Peer reviewed, 2023)Background Retrospective comparative studies suggest a survival benefit after complete local treatment of recurrence (LTR) in renal cell carcinoma (RCC), which may be largely due to an indication bias. Objective To ... -
Localization of CDR2L and CDR2 in paraneoplastic cerebellar degeneration
(Journal article; Peer reviewed, 2020)Objective: Identify the subcellular location and potential binding partners of two cerebellar degeneration‐related proteins, CDR2L and CDR2, associated with anti‐Yo‐mediated paraneoplastic cerebellar degeneration. Methods: ... -
LOCATOR: feature extraction and spatial analysis of the cancer tissue microenvironment using mass cytometry imaging technologies
(Journal article; Peer reviewed, 2023)Motivation Recent advances in highly multiplexed imaging have provided unprecedented insights into the complex cellular organization of tissues, with many applications in translational medicine. However, downstream ... -
Long term clinical disease progression in patients with Parkinson’s disease after STN Deep Brain Stimulation
(Doctoral thesis, 2016-02-12)Background: Parkinson’s disease (PD) is a progressive neurodegenerative disorder with severe longterm impact on patients, their caregivers and on the society in general [1]. The treatment of PD is symptomatic. Surgical ... -
Long term outcomes and causal modelling of compulsory inpatient and outpatient mental health care using Norwegian registry data : protocol for a controversies in psychiatry research project
(Journal article; Peer reviewed, 2023)Objectives: Compulsory mental health care includes compulsory hospitalisation and outpatient commitment with medication treatment without consent. Uncertain evidence of the effects of compulsory care contributes to large ... -
Long-range evolutionary constraints reveal cis-regulatory interactions on the human X chromosome
(Peer reviewed; Journal article, 2015-04-24)Enhancers can regulate the transcription of genes over long genomic distances. This is thought to lead to selection against genomic rearrangements within such regions that may disrupt this functional linkage. Here we test ... -
Long-term effectiveness of cognitive behavior therapy for youth with anxiety disorders: Outcome, predictors and social anxiety
(Doctoral thesis, 2018-06-01)Cognitive behavioral therapy (CBT) has demonstrated favorable long-term outcomes in youth with anxiety disorders in efficacy trials. However, long-term outcomes of CBT delivered in a community setting are uncertain. The ... -
Long-term effectiveness of cognitive behavioral therapy for youth with anxiety disorders
(Peer reviewed; Journal article, 2018-01)Cognitive behavioral therapy (CBT) has demonstrated favorable long-term outcomes in youth with anxiety disorders in efficacy trials. However, long-term outcomes of CBT delivered in a community setting are uncertain. This ... -
Long-term effects of conservative management of vestibular schwannoma on dizziness, balance, and caloric function
(Peer reviewed; Journal article, 2019)Objectives: To study the development of dizziness, caloric function, and postural sway during long-term observation of untreated vestibular schwannoma patients. Study Design: Retrospective review of a prospectively ... -
Long-term effects of fecal microbiota transplantation (FMT) in patients with irritable bowel syndrome
(Journal article; Peer reviewed, 2021)Background We recently found fecal microbiota transplantation (FMT) in irritable bowel syndrome (IBS) patients to be an effective and safe treatment after 3 months. The present follow-up study investigated the efficacy ... -
Long-term follow-up and survivorship after completing systematic surveillance in stage I–III colorectal cancer: who is still at risk?
(Peer reviewed; Journal article, 2015-09)Purpose: In patients with a high life expectancy at the time of surgery for colorectal cancer (CRC), the long-term outcome may be influenced by factors other than their cancer. We aimed to investigate the long-term outcome ... -
Long-term follow-up of IgA nephropathy: clinicopathological features and predictors of outcomes
(Journal article; Peer reviewed, 2023)Background: The establishment of the Oxford classification and newly developed prediction models have improved the prognostic information for immunoglobulin A nephropathy (IgAN). Considering new treatment options, optimizing ... -
Long-term Impact on Gastrointestinal Symptoms, Quality of Life and Nutritional Adequacy after Group Intervention in patients with Irritable Bowel Syndrome
(Master thesis, 2015-05-15)Background: Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder often associated with complex clinical manifestations. There is no cure for IBS, however potent management strategies have been ... -
Long-Term Outcome in a Phase II Study of Regional Hyperthermia Added to Preoperative Radiochemotherapy in Locally Advanced and Recurrent Rectal Adenocarcinomas
(Journal article; Peer reviewed, 2022-01-29)Hyperthermia was added to standard preoperative chemoradiation for rectal adenocarcinomas in a phase II study. Patients with T3-4 N0-2 M0 rectal cancer or local recurrences were included. Radiation dose was 54 Gy combined ... -
Long-Term Outcomes After Open Repair for Ruptured Abdominal Aortic Aneurysm
(Journal article; Peer reviewed, 2020-03-09)Background Early mortality in ruptured abdominal aneurysm (rAAA) is high, but data on long-term outcome are scarce. The aim of this study was to investigate the long-term outcome in survivors after open surgery for rAAA ... -
Long-term recovery after colorectal cancer surgery among the old: a qualitative study
(Journal article; Peer reviewed, 2023)Background Colorectal cancer is the third most frequently diagnosed cancer worldwide, disproportionally affecting older people. With modern treatment, older people are surviving cancer treatment and recovery. However, ...