Blar i Department of Clinical Medicine på tittel
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Polymorphisms of the XRCC1, XRCC3 and XPD genes and risk of colorectal adenoma and carcinoma, in a Norwegian cohort : a case control study
(Peer reviewed; Journal article, 2006-03-16)Background: Genetic polymorphisms in DNA repair genes may influence individual variation in DNA repair capacity, which may be associated with risk of developing cancer. For colorectal cancer the importance of mutations in ... -
Polyvinylpyrrolidone deposition disease : The role of pathology in understanding disease and death in persons with opioid addiction and intravenous drug use
(Doctoral thesis, 2023-10-13)Bakgrunn og målsetting: Polymeren polyvinylpyrrolidon (PVP) er mye brukt som tilsetningsstoff i legemidler. PVP med høy molekylvekt kan ikke utskilles via nyrene og vil derfor opphopes i kroppens vev dersom det administreres ... -
Polyvinylpyrrolidone deposition disease in patients with intravenous opioid use: a case series
(Journal article; Peer reviewed, 2021)The polymer polyvinylpyrrolidone (PVP) is an excipient widely used in prescription drugs. Depending on the molecular weight (MW), parenterally administered PVP may accumulate in various tissues. Consequently, moderate and ... -
Poor Sleep in Patients with Multiple Sclerosis
(Peer reviewed; Journal article, 2012-11-14)Background: Poor sleep is a frequent symptom in patients with multiple sclerosis (MS). Sleep may be influenced by MS-related symptoms and adverse effects from immunotherapy and symptomatic medications. We aimed to study ... -
A population based study on Kidney Cancer in Norway (2008 - 2013). Aspects of biopsy use, surgical treatment and outcome
(Doctoral thesis, 2018-11-02)Aims: The aim of this study was to explore whole nation data, reveal trends and obtain updated numbers on kidney cancer (KC) treatment in the six-year period from 2008- 2013. The field of KC management has undergone ... -
A Porcine Pneumothorax Model for Teaching Ultrasound Diagnostics
(Peer reviewed; Journal article, 2012-05)Objectives: Ultrasound (US) is a sensitive diagnostic tool for detecting pneumothorax (PTX), but methods are needed to optimally teach this technique outside of direct patient care. In training and research settings, porcine ... -
Portal and umbilical venous distribution in the human fetus : a longitudinal ultrasound study
(Doctoral thesis, 2007-06-26)Knowledge of the venous perfusion of the human fetal liver is fragmentary and mainly limited to the umbilical circulation. Current ultrasound technology makes it possible to study blood flow noninvasively and to give new ... -
The position of single-base deletions in the VNTR sequence of the carboxyl ester lipase (CEL) gene determines proteotoxicity
(Journal article; Peer reviewed, 2021)Variable number of tandem repeat (VNTR) sequences in the genome can have functional consequences that contribute to human disease. This is the case for the CEL gene, which is specifically expressed in pancreatic acinar ... -
A positive Real-Time Elastography (RTE) combined with a Prostate Cancer Gene 3 (PCA3) score above 35 convey a high probability of intermediate- or high-risk prostate cancer in patient admitted for primary prostate biopsy
(Peer reviewed; Journal article, 2016-07-08)Background: The standard of care in patients with suspected prostate cancer (PCa) is systematic prostate biopsies. This approach leads to unnecessary biopsies in patients without PCa and also to the detection of clinical ... -
Possible relation between maternal consumption of added sugar and sugar-sweetened beverages and birth weight - time trends in a population
(Peer reviewed; Journal article, 2012-10-24)Background: High birth weight (BW) is a risk factor for later obesity. In Norway, mean BW and proportion of large newborns increased from 1989 to 2000 and subsequently decreased to the 1989 level by 2010. The purpose of ... -
Possible role of intestinal stem cells in the pathophysiology of irritable bowel syndrome
(Journal article; Peer reviewed, 2020)The pathophysiology of irritable bowel syndrome (IBS) is not completely understood. However, several factors are known to play a role in pathophysiology of IBS such as genetics, diet, gut microbiota, gut endocrine cells, ... -
Possible role of peptide YY (PYY) in the pathophysiology of irritable bowel syndrome (IBS)
(Peer reviewed; Journal article, 2020)Irritable bowel syndrome (IBS) is a common gastrointestinal disorder of unknown aetiology for which there is no effective treatment. Although IBS does not increase mortality, it reduces the quality of life and is an economic ... -
Post hepatectomy liver failure (PHLF) – Recent advances in prevention and clinical management
(Journal article; Peer reviewed, 2021)Background Posthepatectomy liver failure (PHLF) is a relatively rare but feared complication following liver surgery, and associated with high morbidity, mortality and cost implications. Significant advances have been ... -
Post resuscitation care – some words of caution and a call for action
(Journal article, 2015-11-04)This fall the European Resuscitation Council (ERC) and the European Cardiology Society (ESC) publish updated post resuscitation care guidelines. For these guidelines to have an impact they must be implemented into daily ... -
Post-PET ultrasound improves specificity of 18F-FDG-PET for recurrent differentiated thyroid cancer while maintaining sensitivity
(Peer reviewed; Journal article, 2015-03-13)Background: Positron emission tomography (PET) using fluor-18-deoxyglucose (18F-FDG) with or without computed tomography (CT) is generally accepted as the most sensitive imaging modality for diagnosing recurrent differentiated ... -
Posterior approach and uncemented stems increases the risk of reoperation after hemiarthroplasties in elderly hip fracture patients
(Peer reviewed; Journal article, 2014)Background — Hemiarthroplasties are performed in great numbers worldwide but are seldom registered on a national basis. Our aim was to identify risk factors for reoperation after fracturerelated hemiarthroplasty in Norway ... -
Posthospitalization follow-up of patients with heart failure using eHealth solutions : restricted systematic review
(Journal article; Peer reviewed, 2022)Background: Heart failure (HF) is a clinical syndrome with high incidence rates, a substantial symptom and treatment burden, and a significant risk of readmission within 30 days after hospitalization. The COVID-19 pandemic ... -
Postoperative Dural Sac Cross-Sectional Area as an Association for Outcome After Surgery for Lumbar Spinal Stenosis: Clinical and Radiological Results From the NORDSTEN-Spinal Stenosis Trial
(Journal article; Peer reviewed, 2023)Study Design: Prospective cohort study. Objective: The aim was to investigate the association between postoperative dural sac cross-sectional area (DSCA) after decompressive surgery for lumbar spinal stenosis and clinical ... -
Postoperative pain management in non-traumatic emergency general surgery: WSES-GAIS-SIAARTI-AAST guidelines
(Journal article; Peer reviewed, 2022)Background Non-traumatic emergency general surgery involves a heterogeneous population that may present with several underlying diseases. Timeous emergency surgical treatment should be supplemented with high-quality ... -
Postoperative treatment after partial nail ablation of ingrown toenails — does it matter what we recommend? A blinded randomised study
(Peer reviewed; Journal article, 2019-05-03)Trial design: In this blinded randomized study we analyzed patient reported outcome of three different treatments after nail surgery. We compared daily footbath with either alkaline or acidic soap or just a simple bandage ...