Browsing Department of Clinical Medicine by Title
Now showing items 184-203 of 1589
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Centralizing a national pancreatoduodenectomy service: striking the right balance
(Journal article; Peer reviewed, 2020)Background Centralization of pancreatic surgery is currently called for owing to superior outcomes in higher-volume centres. Conversely, organizational and patient concerns speak for a moderation in centralization. Consensus ... -
Cerebellar degeneration-related proteins in anti-Yo associated paraneoplastic cerebellar degeneration
(Doctoral thesis, 2021-06-25)Background: Paraneoplastic neurological syndromes (PNS) are rare immune-mediated diseases triggered by cancer, and characterized by circulating onconeural antibodies directed against antigens expressed by neurons and tumor ... -
Cerebral magnetic resonance imaging in children with prenatal drug exposure. Structural and functional aspects of the opioid-exposed brain
(Doctoral thesis, 2018-02-02)Background: Over the last few decades brain imaging studies have made important contributions to our understanding of how prenatal drug exposure can impact normal brain development. The teratogenic potential of alcohol has ... -
Challenges and possible solutions in cross-disciplinary and cross-sectorial research teams within the domain of e-mental health
(Journal article; Peer reviewed, 2021)Purpose: Mental illness presents a huge individual, societal and economic challenges, currently accounting for 20% of the worldwide burden of disease. There is a gap between the need for and access to services. Digital ... -
Chambered warm moist air eyelid warming devices – a review
(Journal article; Peer reviewed, 2021)Background Eyelid warming is an important treatment for meibomian gland dysfunction (MGD). Specialized chambered devices, using warm moist air have been developed. Purpose To critically evaluate the literature on the ... -
Changes in colonic enteroendocrine cells of patients with irritable bowel syndrome following fecal microbiota transplantation
(Journal article; Peer reviewed, 2022)Objectives The aim was to investigate the effect of fecal microbiota transplantation (FMT) on colonic enteroendocrine cells densities in patients with irritable bowel syndrome (IBS). Materials and methods This study ... -
Changes in fecal short-chain fatty acids following fecal microbiota transplantation in patients with irritable bowel syndrome
(Journal article; Peer reviewed, 2020)Background Short‐chain fatty acids (SCFAs) may play a role in the pathophysiology of irritable bowel syndrome (IBS). This study analyzed fecal SCFAs after performing fecal microbiota transplantation (FMT) in the IBS ... -
Changes in Immune Cell Types with Age in Breast are Consistent with a Decline in Immune Surveillance and Increased Immunosuppression
(Journal article; Peer reviewed, 2021)A majority of breast cancers (BC) are age-related and we seek to determine what cellular and molecular changes occur in breast tissue with age that make women more susceptible to cancer initiation. Immune-epithelial cell ... -
Changes in leg pain after bilateral fasciotomy to treat chronic compartment syndrome: a case series study
(Peer reviewed; Journal article, 2013-04-05)Background: Intracompartmental pressure (ICP) as the diagnostic gold standard in the management of chronic compartment syndrome (CCS) is debated. We present a diagnostic protocol in which the decision to operate can be ... -
Changing from a two-tiered to a one-tiered trauma team activation protocol: a before–after observational cohort study investigating the clinical impact of undertriage
(Journal article; Peer reviewed, 2021)Background: The aim of this study was to compare the effect of the change in TTA protocol from a two-tier to one-tier, with focus on undertriage and mortality. Material and methods: A before–after observational cohort ... -
The changing landscape of Fabry disease
(Journal article; Peer reviewed, 2020) -
Changing paradigms of anterior cruciate ligament surgery. From transtibial to a more anatomic approach
(Doctoral thesis, 2015-10-09)The current thesis consists of four papers evaluating results after anterior cruciate ligament reconstruction using two different surgical techniques. Paper I and II evaluate long-term outcomes after a transtibial technique ... -
Characterisation and expression analysis of the Atlantic halibut (Hippoglossus hippoglossus L.) cytokines: IL-1β, IL-6, IL-11, IL-12β and IFNγ
(Peer reviewed; Journal article, 2011-06-05)Genes encoding the five Atlantic halibut (Hippoglossus hippoglossus L.) cytokines; interleukin (IL)-1b, IL-6, IL-11b, IL-12bc, and interferon (IFN) c, were cloned and characterised at a molecular level. The genomic ... -
Characterisation of genomic imbalances in patients with mental retardation
(Doctoral thesis, 2009-03-20)A major cause of mental retardation is chromosomal abnormalities, but due to low sensitivity of conventional chromosomal karyotyping, these abnormalities may stay undetected, and the etiology of the impairment remains ... -
Characteristics and Utility of Fundus Autofluorescence in Congenital Aniridia Using Scanning Laser Ophthalmoscopy
(Peer reviewed; Journal article, 2019)Purpose: To investigate fundus autofluorescence (FAF) and other fundus manifestations in congenital aniridia. Methods: Fourteen patients with congenital aniridia and 14 age- and sex-matched healthy controls were examined. ... -
Characteristics, management and survival of ICU patients with coronavirus disease-19 in Norway, March-June 2020. A prospective observational study
(Journal article; Peer reviewed, 2021)Background: Norwegian hospitals have operated within capacity during the COVID-19 pandemic. We present patient and management characteristics, and outcomes for the entire cohort of adult (>18 years) COVID-19 patients ... -
Characterization of FGD5 expression in primary breast cancers and lymph node metastases
(Peer reviewed; Journal article, 2018)Faciogenital dysplasia 5 (FGD5) amplification drives tumor cell proliferation, and is present in 9.5% of breast cancers. We describe FGD5 expression, assess associations between FGD5 amplification and FGD5 expression, and ... -
Characterization of glomerular extracellular matrix in IgA nephropathy by proteomic analysis of laser-captured microdissected glomeruli
(Peer reviewed; Journal article, 2019-11-14)Background IgA nephropathy (IgAN) involves mesangial matrix expansion, but the proteomic composition of this matrix is unknown. The present study aimed to characterize changes in extracellular matrix in IgAN. Methods In ... -
Characterization of immune cell infiltrate in tumor stroma and epithelial compartments in oral squamous cell carcinomas of Sudanese patients
(Journal article; Peer reviewed, 2021)Background Tumor immune infiltrate has been explored in oral squamous cell carcinoma (OSCC), but studies on simultaneous characterization of multiple immune cell subtypes separately in stromal and intraepithelial tumor ...