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Current role of endoscopic combined intrarenal surgery in the management of renal stones: A scoping review
(Journal article; Peer reviewed, 2023)Introduction: This study aims to review the current role of endoscopic combined intrarenal surgery (ECIRS) in the management of renal stones, with a focus on its efficacy and safety. The secondary outcome was to highlight ... -
Current status of fecal microbiota transplantation for irritable bowel syndrome
(Journal article; Peer reviewed, 2021)Background Irritable bowel syndrome (IBS) is a common gastrointestinal functional disorder. Although IBS is a benign condition, it reduces the quality of life considerably. While there is currently no effective treatment ... -
Current Status of Intravesical Therapies for Bladder Pain Syndrome (BPS): A Narrative Review of Emerging Evidence
(Journal article; Peer reviewed, 2021)Bladder pain syndrome (BPS) is a complex condition, which can have debilitating sequelae for patients. Many elements of BPS remain poorly understood including pathophysiology, diagnosis and treatment. Navigating patient ... -
Current status of nomograms and scoring systems in paediatric endourology: A systematic review of literature
(Journal article; Peer reviewed, 2022)Introduction The incidence of paediatric kidney stone disease is increasing worldwide, with the requirement for endourological interventions mirroring this. Multiple nomograms, grading tools and scoring systems now exist ... -
Current status of thulium fibre laser lithotripsy: an up-to-date review
(Journal article; Peer reviewed, 2021)Objective To perform an up-to-date review to scope the current status of the thulium fibre laser (TFL) in the setting of stone lithotripsy and provide a guide for the clinical urologist. Methods A review of world ... -
Current Status of Ureteric Stents on Extraction Strings and Other Non-cystoscopic Removal Methods in the Paediatric Setting: A Systematic Review on Behalf of the European Association of Urology (EAU) Young Academic Urology (YAU) Urolithiasis Group
(Journal article; Peer reviewed, 2022)Ureteric stents are an important tool in urology and have a wide range of indications. While they offer a number of advantages, limitations remain despite modern advancements. These include discomfort, migration and ... -
Cyclothymic temperament: Associations with ADHD, other psychopathology, and medical morbidity in the general population
(Peer reviewed; Journal article, 2020)Background: Cyclothymic temperament (CT) is an affective disposition often preceding bipolar disorder (BD), and is the most common affective temperament in patients with BD. In depressed patients, CT is a predictor for ... -
Cystatin C proteoforms in chronic kidney disease
(Journal article; Peer reviewed, 2023)Cystatin C, a cysteine protease inhibitor, is used as a biomarker of renal function. It offers several advantages compared to creatinine, and formulas for the estimation of the glomerular filtration rate based on cystatin ... -
Cytokine Patterns as Predictors of Antibiotic Treatment Effect in Chronic Low Back Pain with Modic Changes: Subgroup Analyses of a Randomized Trial (AIM Study)
(Journal article; Peer reviewed, 2023)Objective: Randomized trials testing the effect of antibiotics for chronic low back pain (LBP) with vertebral bone marrow changes on MRI (Modic changes) report inconsistent results. A proposed explanation is subgroups with ... -
Cytokine Patterns in Tuberculosis Infection; IL-1ra, IL-2 and IP-10 Differentiate Borderline QuantiFERON-TB Samples from Uninfected Controls
(Peer reviewed; Journal article, 2016-09-29)Background: Interferon gamma release assays (IGRAs) do not discriminate between active tuberculosis (TB) and latent TB infection (LTBI), which limit their use in TB endemic areas. Subjects with QuantiFERON-TB (QFT) results ... -
Cytokines in Renal Cell Carcinoma : With emphasis on Vascular Endothelial Growth Factor (VEGF) and Interleukin 6 (IL-6)
(Doctoral thesis, 2021-11-12)Aims: In the first three papers we aimed to investigate if different circulating cytokines in blood drawn preoperatively can predict outcome after surgery in patients with renal cell carcinoma (RCC). The last paper aimed ... -
Data entry quality of double data entry vs automated form processing technologies: A cohort study validation of optical mark recognition and intelligent character recognition in a clinical setting
(Journal article; Peer reviewed, 2020)Background and Aims Patient-reported outcome measures (PROMs) are increasingly used in health services. Paper forms are still often used to register such data. Manual double data entry (DDE) has been defined as the gold ... -
DCLK1 Variants Are Associated across Schizophrenia and Attention Deficit/Hyperactivity Disorder
(Peer reviewed; Journal article, 2012-04-23)Doublecortin and calmodulin like kinase 1 (DCLK1) is implicated in synaptic plasticity and neurodevelopment. Genetic variants in DCLK1 are associated with cognitive traits, specifically verbal memory and general cognition. ... -
Deciphering the inflection points to achieve proficiency for each procedure step during training in laparoscopic appendicectomy
(Journal article; Peer reviewed, 2021)Background Laparoscopic appendicectomy is a common procedure early in surgical training. A minimum number is usually required for certification in general surgery. However, data on proficiency are scarce. This study aimed ... -
Decompression alone or with fusion for degenerative lumbar spondylolisthesis (Nordsten-DS): five year follow-up of a randomised, multicentre, non-inferiority trial
(Journal article; Peer reviewed, 2024)Objective To assess whether decompression alone is non-inferior to decompression with instrumented fusion five years after primary surgery in patients with degenerative lumbar spondylolisthesis. Design Five year follow-up ... -
Decompression alone versusdecompression with instrumental fusionthe NORDSTEN degenerativespondylolisthesis trial (NORDSTEN-DS); study protocol for a randomized controlled trial
(Peer reviewed; Journal article, 2019-01-05)Background: Fusion in addition to decompression has become the standard treatment for lumbar spinal stenosis with degenerative spondylolisthesis (DS). The evidence for performing fusion among these patients is conflicting ... -
Decompression with or without Fusion in Degenerative Lumbar Spondylolisthesis
(Journal article; Peer reviewed, 2021)BACKGROUND In patients with lumbar spinal stenosis and degenerative spondylolisthesis, it is uncertain whether decompression surgery alone is noninferior to decompression with instrumented fusion. METHODS We conducted an ... -
Decreased survival of medial pivot designs compared with cruciate-retaining designs in TKA without patellar resurfacing.
(Journal article; Peer reviewed, 2020)Background The medial pivot TKA design was introduced in the 1990s. These are fixed-bearing, medial-conforming implants with virtually no translation in the medial part of the knee, in contrast to the flat lateral part ... -
Default-mode network functional connectivity is closely related to metabolic activity
(Peer reviewed; Journal article, 2015-06)Over the last decade, the brain's default-mode network (DMN) and its function has attracted a lot of attention in the field of neuroscience. However, the exact underlying mechanisms of DMN functional connectivity, or more ... -
Defective i⁶A37 Modification of Mitochondrial and Cytosolic tRNAs Results from Pathogenic Mutations in TRIT1 and Its Substrate tRNA
(Peer reviewed; Journal article, 2014-06-05)Identifying the genetic basis for mitochondrial diseases is technically challenging given the size of the mitochondrial proteome and the heterogeneity of disease presentations. Using next-generation exome sequencing, we ...