Browsing Department of Clinical Medicine by Title
Now showing items 642-661 of 2116
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Efficient extraction of small microplastic particles from rat feed and feces for quantification
(Journal article; Peer reviewed, 2023)To date, microplastic is ubiquitously encountered in the environment. Studies analyzing microplastic in terrestrial ecosystems, including animal feces and feed, are few. Microplastic quantification method validation and ... -
EFSUMB recommendations for gastrointestinal ultrasound part 3: Endorectal, endoanal and perineal ultrasound
(Peer reviewed; Journal article, 2019)This article represents part 3 of the EFSUMB Recommendations and Guidelines for Gastrointestinal Ultrasound (GIUS). It provides an overview of the examination techniques recommended by experts in the field of endorectal/endoanal ... -
EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1
(Journal article; Peer reviewed, 2021)The Hippo pathway is frequently dysregulated in cancer, leading to the unrestrained activity of its downstream targets, YAP/TAZ, and aberrant tumor growth. However, the precise mechanisms leading to YAP/TAZ activation in ... -
eHealth interventions to support colorectal cancer patients’ self-management after discharge from surgery : an integrative literature review
(Journal article; Peer reviewed, 2024)Introduction: Colorectal cancer (CRC) creates elevated self-management demands and unmet support needs post-discharge. Follow-up care through eHealth post-primary surgery may be an effective means of supporting patients’ ... -
Elderly Patients in the Intensive Care Unit
(Journal article; Peer reviewed, 2021)Very old intensive care unit (ICU) patients, aged ≥ 80 years, are by no mean newcomers, but during the last decades their impact on ICU admissions has grown in parallel with the increase in the number of elderly persons ... -
Elderly Patients With No Previous Psychiatric History: Suicidality and Other Factors Relating to Psychiatric Acute Admissions
(Journal article; Peer reviewed, 2020)Background: The common recommendation that adults with onset of mental illness after the age of 65 should receive specialised psychogeriatric treatment is based on limited evidence. Aims: To compare factors related to ... -
Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries
(Journal article; Peer reviewed, 2022)Background The 2015 Lancet Commission on global surgery identified surgery and anaesthesia as indispensable parts of holistic health-care systems. However, COVID-19 exposed the fragility of planned surgical services around ... -
Electric field causes volumetric changes in the human brain
(Peer reviewed; Journal article, 2019)Recent longitudinal neuroimaging studies in patients with electroconvulsive therapy (ECT) suggest local effects of electric stimulation (lateralized) occur in tandem with global seizure activity (generalized). We used ... -
Electroconvulsive therapy for bipolar disorder depression. Effects on depressive symptoms and cognitive function
(Doctoral thesis, 2014-11-28)Background: Treating the depressive state of bipolar disorder (BD) is challenging. Pharmacological treatments often have poor outcomes. Electroconvulsive therapy (ECT) is generally considered to be the most effective acute ... -
Electroconvulsive therapy triggers a reversible decrease in brain N-acetylaspartate
(Journal article; Peer reviewed, 2023)Introduction: Based on previous research on electroconvulsive therapy (ECT) we have proposed a model where disruption, potentiation, and rewiring of brain networks occur in sequence and serve as the underlying therapeutic ... -
Electrolyte profiles with induced hypothermia: A sub study of a clinical trial evaluating the duration of hypothermia after cardiac arrest
(Journal article; Peer reviewed, 2022)Background Electrolyte disturbances can result from targeted temperature treatment (TTM) in out-of-hospital cardiac arrest (OHCA) patients. This study explores electrolyte changes in blood and urine in OHCA patients treated ... -
Elevated Ambulatory Blood Pressure Measurements are Associated with a Progressive Form of Fabry Disease
(Journal article; Peer reviewed, 2021)Introduction Published data on hypertension incidence and management in Anderson–Fabry disease are scant and the contribution of elevated blood pressure to organ damage is not well recognized. Aim Therefore, we have ... -
Elevated levels of CXCL10 in the Periodic Fever, Aphthous stomatitis, Pharyngitis and cervical Adenitis syndrome (PFAPA) during and between febrile episodes; an indication of a persistent activation of the innate immune system
(Peer reviewed; Journal article, 2013-10-17)Background: The Periodic Fever, Aphthous stomatitis, Pharyngitis and cervical Adenitis syndrome (PFAPA) is the most common periodic fever syndrome in childhood. Clinically, PFAPA may resemble autoinflammatory diseases, but ... -
Elevated microsatellite alterations at selected tetranucleotides (EMAST) is not attributed to MSH3 loss in stage I-III colon cancer: An automated, digitalized assessment by immunohistochemistry of whole slides and hot spots
(Peer reviewed; Journal article, 2019-12)INTRODUCTION: EMAST is a poorly understood form of microsatellite instability (MSI) in colorectal cancer (CRC) for which loss of MSH3 has been proposed as the underlying mechanism, based on experimental studies. We aimed ... -
Elevated microsatellite alterations at selected tetranucleotides in early-stage colorectal cancers with and without high-frequency microsatellite instability: same, same but different?
(Peer reviewed; Journal article, 2016-07)Microsatellite instability (MSI) is associated with better prognosis in colorectal cancer (CRC). Elevated microsatellite alterations at selected tetranucleotides (EMAST) is a less-understood form of MSI. Here, we aim to ... -
Elevated plasma interleukin 6 predicts poor response in patients treated with sunitinib for metastatic clear cell renal cell carcinoma
(Peer reviewed; Journal article, 2019)Introduction: Clear cell renal cell carcinoma (ccRCC) is the most common type among renal cell carcinomas, and anti-angiogenic treatment is currently first line therapy in metastatic ccRCC (mccRCC). Response rates and ... -
Embryonic Stem Cells Can Generate Oral Epithelia under Matrix Instruction
(Journal article; Peer reviewed, 2023)We aimed to investigate whether molecular clues from the extracellular matrix (ECM) can induce oral epithelial differentiation of pluripotent stem cells. Mouse embryonic stem cells (ESC) of the feeder-independent cell line ... -
Emergency intraosseous access in a helicopter emergency medical service: a retrospective study
(Peer reviewed; Journal article, 2010-10-07)Intraosseous access (IO) is a method for providing vascular access in out-of-hospital resuscitation of critically ill and injured patients when traditional intravenous access is difficult or impossible. Different intraosseous ... -
Emergency resuscitative thoracotomy performed in European civilian trauma patients with blunt or penetrating injuries: a systematic review
(Peer reviewed; Journal article, 2015)Purpose: Emergency resuscitative thoracotomy (ERT) is a lifesaving procedure in selected patients. Indications are still being debated, but outcome in blunt trauma is believed to be poor. Recent reports from European ... -
Emergency surgery in the elderly: the balance between function, frailty, fatality and futility
(Peer reviewed; Journal article, 2015-02-03)Becoming old is considered a privilege and results from the socioeconomic progress and improvements in health care systems worldwide. However, morbidity and mortality increases with age, and even more so in acute onset ...