Blar i Department of Clinical Medicine på tittel
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Epithelial to Mesenchymal Transition of a Primary Prostate Cell Line with Switches of Cell Adhesion Modules but without Malignant Transformation
(Peer reviewed; Journal article, 2008-10-13)Background: Epithelial to mesenchymal transition (EMT) has been connected with cancer progression in vivo and the generation of more aggressive cancer cell lines in vitro. EMT has been induced in prostate cancer cell lines, ... -
Epithelial-to-mesenchymal transition in clear cell renal cell cancer and renal fibrosis
(Doctoral thesis, 2019-01-16)Background: Clear cell renal cell cancer (ccRCC) is a common cancer in humans and still has a high mortality. Chronic kidney disease (CKD) is a worldwide public health issue due to its increasing incidence and high morbidity ... -
The epithelial–mesenchymal transition regulators Twist, Slug, and Snail are associated with aggressive tumour features and poor outcome in prostate cancer patients
(Journal article; Peer reviewed, 2021)The prognostic importance of transcription factors promoting epithelial–mesenchymal transition (EMT) and angiogenesis has not been well explored in prostate cancer patients with long follow-up, nor the interplay between ... -
Er angst, apati og kognitiv sviktprofil assosiert med sykdomsprogresjon ved mild demens? Med hovedfokus på demens med Lewylegemer
(Doctoral thesis, 2018-10-12)Background Dementia is a major public health problem in all parts of the world, and due to an aging population, the prevalence of dementia is growing. Two of the most frequent forms of dementias are Alzheimer`s disease ... -
Ernæringsstatus hos voksne pasienter med inflammatorisk tarmsykdom som får biologisk behandling ved Sørlandet sykehus
(Master thesis, 2018-06-22)Rationale: Patients with inflammatory bowel disease (IBD) belong to a high-risk group for malnutrition [1]. The aim was to evaluate if «Nutritional Risk Screening 2002» (NRS 2002) detects patients at nutritional risk, and ... -
Erosion or normal variant? 4-year MRI follow-up of the wrists in healthy children
(Journal article; Peer reviewed, 2016)Background A large proportion of healthy children have wrist changes on MRI, namely carpal depressions, findings that have been described as pathological in children with juvenile idiopathic arthritis. Objective We ... -
Errors in medicine: punishment versus learning medical adverse events revisited - expanding the frame
(Journal article; Peer reviewed, 2023)Purpose of review : Despite healthcare workers’ best intentions, some patients will suffer harm and even death during their journey through the healthcare system. This represents a major challenge, and many solutions have ... -
Esophageal perforation: Diagnostic work-up and clinical decision-making in the first 24 hours
(Peer reviewed; Journal article, 2011-10-30)Abstract Esophageal perforation is a rare and potentially life-threatening condition. Early clinical suspicion and imaging is important for case management to achieve a good outcome. However, recent studies continue to ... -
The ESSO core curriculum committee update on surgical oncology
(Journal article; Peer reviewed, 2021)Introduction Surgical oncology is a defined specialty within the European Board of Surgery within the European Union of Medical Specialists (UEMS). Variation in training and specialization still occurs across Europe. There ... -
Establishing quality indicators for prehospital advanced airway management: a modified nominal group technique consensus process
(Journal article; Peer reviewed, 2021)Background: Prehospital advanced airway management is a complex intervention composed of numerous steps, interactions, and variables that can be delivered to a high standard in the prehospital setting. Standard research ... -
Establishing reliable MR spectroscopy techniques for measuring GABA and Glutathione in the human brain
(Doctoral thesis, 2018-05-03)Background: Proton MR spectroscopy (MRS) is a well-established method for measuring the relative concentration of a wide range of metabolites in the human brain noninvasively. Lately, more advanced spectroscopic techniques, ... -
Establishment of a bioluminescence model for microenvironmentally induced oral carcinogenesis with implications for screening bioengineered scaffolds.
(Peer reviewed; Journal article, 2015)Background: Microenvironmental cues play a major role in head and neck cancer. Biodegradable scaffolds used for bone regeneration might also act as stimulative cues for head and neck cancer. The purpose of this study was ... -
Establishment of a novel cancer cell line derived from vulvar carcinoma associated with lichen sclerosus exhibiting a fibroblast-dependent tumorigenic potential
(Journal article; Peer reviewed, 2020)Vulvar squamous cell carcinoma associated with lichen sclerosus (VLS-VSCC) are rare tumors but with higher recurrence and worse prognosis than other types of VSCC. Lack of experimental models has limited the search for ... -
Estimation of Preanalytical Uncertainty in Clinical Chemistry
(Doctoral thesis, 2013-05-27)Preanalytical uncertainty is attributable to variations in blood sample collection and sample handling before analysis. The aim of this study was to establish a modelling framework for estimating preanalytical uncertainty. ... -
Estradiol measurement in translational studies of breast cancer
(Peer reviewed; Journal article, 2015-07)Plasma estrogen measurement with use of radioimmunoassays has been instrumental in the development of aromatase inhibitors for endocrine therapy of postmenopausal breast cancer. However, due to low plasma estrogen ... -
Ethical challenges in nursing homes - staff's opinions and experiences with systematic ethics meetings with participation of residents' relatives.
(Peer reviewed; Journal article, 2015-04-28)Background Many ethical problems exist in nursing homes. These include, for example, decision-making in end-of-life care, use of restraints and a lack of resources. Aims The aim of the present study was to investigate ... -
Ethical challenges, decision-making and end-of-life care in nursing homes
(Doctoral thesis, 2017-02-13)Background: Many nursing home residents suffer from multimorbidity, frailty and dementia. A number of ethical challenges are connected to living and dying in nursing homes. Objective/purpose: This thesis investigates ethical ... -
European Burns Association guidelines for the management of burn mass casualty incidents within a European response plan
(Journal article; Peer reviewed, 2023)Background: A European response plan to burn mass casualty incidents has been jointly developed by the European Commission and the European Burn Association. Upon request for assistance by an affected country, the plan ... -
A European multicenter study on systematic ethics work in nursing homes
(Peer reviewed; Journal article, 2016)Background: There are many existing ethical challenges in nursing homes. Although different methods and approaches to discussing the ethical challenges have been established, systematic ethics work is not yet a standard ... -
European neuroborreliosis: Long term follow-up
(Doctoral thesis, 2012-06-15)Lyme disease is the most common human tick borne disease in the northern hemisphere, and the southern coastline of Norway is a high endemic region regarding Lyme disease. European Lyme neuroborreliosis (LNB) often presents ...